Autogenous Tooth Bone Graft Versus Allogeneic Bone Graft Around Dental Implant in Aesthetic Zone
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 24
- 试验地点
- 1
- 主要终点
- labial bone thickness
研究概览
简要总结
24 patienta with non restorable anterior teeth underwent extraction with immediate implant installation using bone grafts either autogenous tooth bone graft or allogenic bone graft Autogenous tooth bone graft group (study group): 12 patients will have immediate implant placement with autogenous tooth bone graft.
• Allogeneic bone graft group (control group): 12 patients will have immediate implant placement with allogeneic bone graft (demineralized freeze dried bone allograft - cortico cancellous).
详细描述
24 patienta with non restorable anterior teeth underwent extraction with immediate implant installation randomized to two groups Autogenous tooth bone graft group (study group): 12 patients will have immediate implant placement with autogenous tooth bone graft.
• Allogeneic bone graft group (control group): 12 patients will have immediate implant placement with allogeneic bone graft (demineralized freeze dried bone allograft - cortico cancellous).
preparation of autogenous tooth bone graft Any restorations, caries, cementum, periodontal ligament and pulp tissue will be removed .The tooth will be grinded using dental bone mill and bone crusher Tooth particles will be sieved to particles size 300 to 1200 microns. The sorted particles will be immersed in 70 % ethanol and 5% Peracetic acid* in a sterile container for 10 minutes to remove any soft tissue remnants, bacteria and smear layer (defatting and sterilization).
Tooth particles will be demineralized using 2% HNO3for 20 minutes to expose the dentine organic matrix.
The bacteria-free particulate dentin will be washed with phosphate buffered saline‡ twice for 5 minutes to restore the PH balance to 7.4. In the same setting, surgical procedure after atraumatic extraction immediate implant willbe inserted according to dimensions taken from CBCT and jumbing gap will be filled with bone graft according to randomization
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients with non restorable maxillary anterior teeth need to be extracted.
- •Thin labial plate of bone of the tooth to be extracted.
- •Patients age above 20years old.
- •Good oral hygiene.
- •No signs of acute infection or inflammation
排除标准
- •Prior radiation therapy.
- •Soft and hard tissue pathology at the operation site.
- •Any relevant systemic disease or medication that might compromise bone healing.
结局指标
主要结局
labial bone thickness
时间窗: 6 months
measuring thickness of labial bone labial to the implant
marginal bone loss
时间窗: 6 months
次要结局
- bone density around dental implant(6 months)
- implant secondary stability(6 months)
- implant success(6 months)
研究者
Diab Abdel Gaied Diab Ghanem Mohammed
principal investigator
Tanta University