Intraoperative Transesophageal echo-cardiographic parameters to predict Post Reperfusion Syndrome during Living Donor Liver Transplantation: A Prospective Study
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Transesophageal echocardiographic parameter to predict post reperfusion syndrome during living donor liver transplantation
研究概览
简要总结
Patients undergoing liver transplant frequently display considerable physiological changes during the procedures as a result of both the disease process and the surgery. Haemodynamic changes occurring during liver transplantation are severe and rapid. Transoesophageal echocardiography is a minimally invasive monitor that provides real-time visual information regarding dynamic function of heart, volume status, contractility, regional wall motion. Intraoperative transoesophageal echocardiography has been standard practice for cardiac surgical procedures for more than 2 decades but its use during liver transplant is gaining popularity in recent years. Society for advancement of transplant anesthesia suggests, that transoesophageal echocardiography use in liver transplant recipients is effective and safe.1 Vital information which can be gathered from standard transoesophageal echocardiography views includes biventricular function, valvular function, volume status, pericardial abnormalities, intra-cardiac thrombus, pulmonary embolism, ventricular outflow obstruction, cardiac tamponade.
As per our literature search, intraoperative transesophageal echocardiographic parameters have never been studied to predict the post reperfusion syndrome during living donor liver transplantation. Hence, we are conducting this study to find the intraoperative transesophageal echocardiographic parameters which can predict the post reperfusion syndrome during living donor liver transplantation.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)(—)
- 性别
- All
入选标准
- •All patients undergoing LDLT in whom transesophageal echocardiography probe will be inserted Age > 18 years.
排除标准
- •Patient refusal Patients undergoing double transplant at same setting.
- •Patients with Acute Liver Failure Previous history of oesophageal pathology (esophageal stricture, cancer, diverticulum, laceration, > grade 3 oesophageal varices, Gastric varices, active esophagitis) or recent esophageal surgery.
- •History of recent (< 1 month) upper gastro-intestinal bleed.
结局指标
主要结局
Transesophageal echocardiographic parameter to predict post reperfusion syndrome during living donor liver transplantation
时间窗: Baseline after induction | 10 minutes after reperfusion | After abdominal closure
次要结局
- Transesophageal echocardiographic parameter to predict time to achieve hemodynamic stability(Baseline after induction)
