Short Pulse and Q-switched ND-YAG Laser With Topical Carbon Versus Fractional CO2 Laser in Treatment of Enlarged Facial Pores: A Split-face Comparative Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- the percentage of decrease in size of enlarged facial pores assessed clinically and by dermoscopy
研究概览
简要总结
Facial pores are visible topographic features of the skin that reflect openings of pilosebaceous follicles, that may be enlarged causing distress to some individuals. Many patients desire treatment for this condition, which can be an early sign of skin aging. Therapeutic modalities include intense pulsed light, radiofrequency, dermabrasion, oral and topical retinoids, as well as chemical peeling. Lasers, as fractional CO2, short pulse and Q-switched Nd-YAG, can potentially be used in treatment of wide pores.
This study aims at the assessment and comparison of therapy with short pulsed and Q-switched Nd-YAG laser plus topical carbon with fractional CO2 laser in the management of wide facial pores.
详细描述
topical carbon cream will be applied to one side of the face in patients with wide facial pores, followed by 2 passes of short pulse 1064 ND:YAG laser, then one pass of Q-switched ND-YAG laser.
fractional CO2 laser will be performed to the other half of the face. the patients will receive 2 treatment sessions
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Participants who are more than 18 years old with the large facial pores and are aware of their problem and seeking treatment
排除标准
- •• Previous laser therapy, chemical peeling, microdermabrasion or cosmetic procedure for the face.
- •Patients with any contraindication to laser therapy such as photosensitive diseases, skin malignancies, patients on oral retinoids.
- •Keloid-forming tendency.
- •Local or systemic treatment for skin pores in the previous 3 months
- •Connective tissue disease or the use of immunosuppressive medications.
- •Pregnancy.
- •Present or past history of herpes labialis.
结局指标
主要结局
the percentage of decrease in size of enlarged facial pores assessed clinically and by dermoscopy
时间窗: 2 months
次要结局
未报告次要终点
研究者
Dina Saadi
principal investigator
Cairo University