Body Parameters as an Independent Predictor of Acute Pancreatitis: A Propensity Score-matched Case-control Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 1,662
- 试验地点
- 1
- 主要终点
- Comparisons of variables according to AP severity
研究概览
简要总结
This study is to assess the predictive significance of visceral adipose tissue (VAT) and visceral adipose tissue /skeletal muscle tissue ratio (VAT/SMT ratio) for the prognosis in acute pancreatitis (AP) patients.
详细描述
Acute pancreatitis (AP) is a sudden inflammation of the pancreas. However, one-fifth of patients may develop severe complications with a mortality between 10%-20% It remains a difficulty to find an effective method for prediction of severity of AP at early stage.
It is well-established that obesity (defined as body mass index[BMI]>30kg/m2 by the World Health Organization) is a risk factor for AP and increases the incidence of systemic complication, motality. There are a lot of parameters related to saropenic obesity, including areas of visceral adipose tissue (VAT), subcutaneous adipose tissue (SAT), skeletal muscle tissue (SMT), and VAT/SMT ratio. it is unclear which parameter is the best predictor of severe AP. Thus, this study is aimed to investigate the association between these parameters and AP severity and find the best predictor of AP.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 100 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •diagnosed with AP
- •age >18 years
排除标准
- •age<18years
- •missing data in the electronic medical record
- •history of AP
结局指标
主要结局
Comparisons of variables according to AP severity
时间窗: the physical examination data in the year of 2017
Comparisons of variables according to AP severity by one-way analysis of variance (ANOVA) and Likelihood Ratio
Relationships between VAT and severity outcomes Relationships between VAT and severity outcomes Relationships between VAT and severity outcomes Relationships between body parameters and severity outcomes
时间窗: the physical examination data in the year of 2017
Relationships between VAT and severity outcomes by Likelihood Ratio
次要结局
未报告次要终点
