Evaluation of musculoskeletal pain and collagen production in patients with vitamin C supplemented osteogenesis imperfecta: pilot study of a randomized controlled trial

niversidade do Sul de Santa Catarina0 个研究点开始时间: 2019年9月27日最近更新: 2023年5月29日

适应症

试验速览

暂无简介。

•Patients with OI (types I, III and IV) and without other associated diseases. Age range from zero to 18 years. Patients who underwent intravenous disodium pamidronate treatment cycles at the HIJG every 2, 3, 4, or 6 months between January and December 2018. Patients who had conditions for oral medication administration. Patients who do not use continuous analgesics, continuous anti-inflammatory drugs or antidepressants for pain control or other medical indication.

•PParticipants who did not attend the hospital for disodium pamidronate administration. Participants who presented temporary or permanent suspension of disodium pamidronate administration during the data collection period. Participants who did not have blood samples collected during the first or second data collection. Participants who did not return for the second data collection. Participants who used continuous analgesics, continuous anti-inflammatory drugs and antidepressants for pain control or other medical indication after the first data collection. Participants reporting inadequate vitamin C supplementation between data collections.

发起方

niversidade do Sul de Santa Catarina