The Relation Between Common Carotid Artery Diameter and Central Venous Pressure for Assessment of Intravascular Fluid Status After Major Surgeries: An Observational Study
试验速览
- 阶段
- 不适用
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Common Carotid Artery diameter at expiration (millimetre)
研究概览
简要总结
Recently, bedside ultrasound has become an important tool for the simple and non-invasive hemodynamic assessment of critically ill patients. This applies not only to echocardiography but also to ultrasound of large extra-thoracic veins. The sonography can provide real time assessment of the vascular system and hemodynamic status at the bedside.
To our knowledge, there is one report about the association between sonographically assessed carotid artery diameter and intravascular volume, which raised recommendation for further studies including the interplay between carotid geometry and intravascular fluid status.
Aim of the study:
The aim of this work is to evaluate the accuracy of noninvasive techniques for assessment of intravascular volume status by Sonographic assessment of both the common carotid artery diameter (CCA) and the central venous pressure (CVP) in response to a bolus of crystalloid solution infusion and to find the correlation between CCA diameter and CVP as the primary outcome in adults patients after major surgeries who needs close assessment and maintenance of the intravascular volume status.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Male and female patients (age 20-60 years).
- •ASA physical status I and II
- •Patients who are able to breathe spontaneously and lie supine.
- •Patients who have CVP catheter (subclavian or internal jugular vein).
排除标准
- •History of carotid artery surgery
- •Significant cardiac disease (cardiomyopathy and/or moderate to severe valvular heart lesion).
- •Significant hepatic disease (Child-Pugh score B or C ).
- •Renal failure.
- •Obesity: BMI ˃ 30 kg/m2
- •Need for mechanical ventilation.
- •Unstable vital signs during the process of sonography (e.g. the patients on vasoactive drugs)
结局指标
主要结局
Common Carotid Artery diameter at expiration (millimetre)
时间窗: 5 minutesafter fluid bolus infusion
common carotid artery internal diameter changes songraphically measured to assess intravenous resuscitation
Central venous pressure (centimetre water)
时间窗: 5 minutes after fluid bolus infusion
Central venous pressure changes measured to assess intravenous resuscitation
次要结局
未报告次要终点
研究者
Samaa A. Kasem
Associate professor
Beni-Suef University