NCT00953628已完成4 期
Endometrial Advancement After Rec or u-HCG Triggering
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 130
- 试验地点
- 1
- 主要终点
- endometrium histology on the day of OPU
研究概览
简要总结
The purpose of this study is to investigate any potential advantages of replacing human chorionic gonadotropin (uhCG) with recombinant human chorionic gonadotropin (recHCG) for final oocyte maturation with regard to Ovarian hyperstimulation syndrome (OHSS)pathophysiology, endometrium receptivity and embryo quality and clinical pregnancy.
详细描述
Biopsies of endometrium were taken in different groups Pregnancy rates were compared among defferent groups
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 20 Years 至 36 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Less than 36 years old
- •Male or tubal infertility
- •FSH<12 on day 3
排除标准
- •Endometriosis stage 3 & 4
研究组 & 干预措施
o Group A=uHCG ovul trig
Active Comparator
HCG for triggering
干预措施: 10000 IU urinary HCG (Drug)
o Group B=recHCG ovul trig
Experimental
recombinant HCG for triggering
干预措施: 250 mcg recombinant HCG (Drug)
结局指标
主要结局
endometrium histology on the day of OPU
时间窗: day of oocytre pick up
次要结局
- pregnancy rate(14 days after oocyte pick up)
研究者
Papanikolaou Evangelos
Lecturer Aristotle University Greece
Universitair Ziekenhuis Brussel
研究点 (1)
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