Glycemic and Insulinemic Responses of Low-Carbohydrate Snack Foods
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 10
- 试验地点
- 2
- 主要终点
- Postprandial glucose response
研究概览
简要总结
The aim of this study is develop recipes containing CHO less than ICR, prepare new snacks alternatives that could be consumed without need for additional insulin doses, and evaluate the glycemic and insulinemic responses of these recipes. A randomized crossover trial will include 15 healthy adults aged 19-30 years. All participants will consume 3 test foods and reference food (glucose solution, 2 times) in a random order. Blood samples will be collected at time points 0,15, 30, 45, 60, 90 and 120 min. Glucose and insulin analyzes will be performed from blood samples. The results of these time points will be marked on the chart and the incremental area under the curve (iAUC) will be calculated for both glucose and insulin.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 19 Years 至 30 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy volunteer
- •Normal body weight (18.5-25 kg / m2 BMI)
- •19-30 years old
排除标准
- •use of tobacco,
- •weight change of >5 kg in the last 3 months
- •the presence of any chronic disease or lactose intolerance,
- •regular medicine use,
- •pregnancy or lactation,
- •performing competitive sports or endurance sports,
- •fasting plasma glucose concentration >100 mg / dL,
- •the presence of eating disorder,
- •sensitivity or allergies to any food that used in the study
结局指标
主要结局
Postprandial glucose response
时间窗: two hours postprandial period
Postprandial glucose response will be quantified as incremental area under the curve (iAUC) (mg/dL x minutes), which is calculated according to the trapezoidal rule by using blood glucose values at time points 0, 15, 30, 45, 60, 90, and 120 minutes.
Postprandial insulin response
时间窗: two hours postprandial period
Postprandial insulin response will be quantified as incremental area under the curve (iAUC) (mg/dL x minutes), which is calculated according to the trapezoidal rule by using blood glucose values at time points 0, 15, 30, 45, 60, 90, and 120 minutes.
次要结局
未报告次要终点
研究者
Zeynep Caferoglu, PhD
Assistant Professor Doctor
TC Erciyes University