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临床试验/NCT06790901
NCT06790901已完成不适用

EVALUATION of PEROPERATIVE ATELECTASIS with LUNG ULTRASOUND SCORE in GENERAL ANAESTHESIA MAINTENANCE METHODS

Zonguldak Bulent Ecevit University1 个研究点 分布在 1 个国家目标入组 90 人开始时间: 2023年9月15日最近更新:

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
90
试验地点
1
主要终点
Peroperative Atelectasis

研究概览

简要总结

We know that respiratory functions of patients are affected under general anaesthesia. Although there are many underlying causes of ventilation-perfusion mismatch in the airways, the main cause is atelectasis during general anaesthesia.

Atelectasis occurs in almost all patients receiving general anaesthesia. The main cause of atelectasis is the loss of muscle tone during general anaesthesia. Postoperative atelectasis was described in the last century. It is defined as the closure of the alveoli due to a decrease in inspiratory force and collapse of the lung and the resulting loss of aeration.

Inhalation anaesthetics have been shown to cause hypoxic pulmonary vasoconstriction in studies. However, not all inhalation anaesthetics affect the airways in the same way.

In patients who will undergo surgical procedures under different general anaesthesia maintenance methods, conditions that disrupt the ventilation-perfusion balance in the lung peroperatively can be diagnosed and monitored early, easily and inexpensively by lung ultrasonography.

Lung ultrasound is a noninvasive, reliable, reliable, radiation-free imaging method that provides instantaneous imaging at the bedside. Lung ultrasound score is a scoring system that provides scoring of the loss of ventilation in the lung. For this purpose, it was aimed to divide both lung tissues into 12 areas and to give a score between 0 and 3 points and to show the severity of the loss of aeration according to the resulting total score.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • 18-65 years old ASA I-II Surgical procedure time between 2 hours and 5 hours in supine position Patients who will undergo rhinoplasty, septorhinoplasty operation Patients whose consent was obtained with an informed consent form

排除标准

  • Those with a history of malignant hyperthermia,
  • People with alcohol or drug addiction,
  • Presence of dementia or confusion,
  • Uncooperative patients,
  • Those with respiratory disease,
  • Those with coronary artery disease, congestive heart failure,
  • Patients with unstable blood pressure,
  • Significant anaemia, liver or kidney disease,
  • Women during pregnancy or lactation,
  • Allergy to anaesthetic agents,
  • Body mass index (BMI) >30 kg/m2,
  • Those with sepsis or bacterial infection, Body temperature below 35°C and above 38°C at control value

结局指标

主要结局

Peroperative Atelectasis

时间窗: from induction to postoperative 1st hour

次要结局

未报告次要终点

研究者

发起方
Zonguldak Bulent Ecevit University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Oguzhan Karayaka

MD

Zonguldak Bulent Ecevit University

研究点 (1)

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