Training Cognition in patients with advanced Parkinson's Disease (TrainParC-Advanced) - Feasibility, Effects and Prediction of Responsiveness of a digital cognitive training - TrainParC-Advanced

niversität zu Köln0 个研究点目标入组 140 人开始时间: 2022年11月21日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•1. Patients with IPD according to the UK Brain Bank criteria (Gibb & Lees, 1988).
•2. Advanced stage disease, defined as IPD patients who meet = 1 of the 5-2-1 criteria: 5 intakes of levodopa tablets per day and/or 2 hours of OFF time per day and/or 1 hour of troublesome dyskinesia per day (Antonini et al., 2018; Santos-García et al., 2020) or receive pump therapy
•3. Patients who are cognitively unimpaired or have only suspected MCI (MoCA > 21 points; Dalrymple-Alford et al., 2010)
•4. Patients who have stable medication within the last 4 weeks before training and between baseline and posttest
•5. Age: 18 years and older; all genders
•6. German as native language or sufficiently good knowledge of German
•7. Access to a computer, laptop or tablet with internet access

•1. Dementia according to level 1 diagnostics (MoCA < 21 points; Dalrymple-Alford et al., 2010)
•2. Major depression (BDI-II = 29 points; Beck et al., 1996).
•3. Epilepsy and other diseases with seizure-like manifestations and/or disorders of consciousness (ICD-10 G40)
•4. Other neurological or psychiatric illness; acute life-threatening illness (self-report in medical history and physician's letters).

发起方

niversität zu Köln