Comparison Between High-density Electroencephalography and Conventional Electroencephalography to Diagnose the Presence of Consciousness in Post-anoxic Comatose Patients
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Number of patients who recovered and who presented a mismatch negativity in high-density but not conventional electroencephalography
研究概览
简要总结
The purpose of this study is to measure whether high-density electroencephalography can improve the detection of electrophysiological signs of awareness compared to conventional electroencephalography in post-anoxic comatose patients
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •post anoxic coma
- •over 18 years old
- •agreement from families
- •alive 4 days after the beginning of coma
排除标准
- •traumatic coma
- •non-traumatic but not anoxic coma
- •patients with severe comorbidity previous to coma
- •refusal of families to participate to the study
- •contraindication to a high-density electroencephalography exam
研究组 & 干预措施
electroencephalography recording
Cerebral measurements from high-density and conventional electroencephalography are recorded simultaneously
干预措施: high-density electroencephalography (Device)
electroencephalography recording
Cerebral measurements from high-density and conventional electroencephalography are recorded simultaneously
干预措施: Conventional electroencephalography (Device)
结局指标
主要结局
Number of patients who recovered and who presented a mismatch negativity in high-density but not conventional electroencephalography
时间窗: 4 days after the beginning of coma
mismatch negativity is an electrophysiological response recorded after the presentation of deviant auditory stimulations Recovery is assessed 1 month after the beginning of coma
次要结局
- Number of patients who recovered and who presented a mismatch negativity in high-density but not conventional electroencephalography(19 days after the beginning of coma)
- Number of patients who recovered and who presented a mismatch negativity in high-density but not conventional electroencephalography(7 days after the beginning of coma)