Effectiveness Of Single Doses Of Ibuprofen In Patients With Osteoarthritis Of The Knee
Phase 1
Completed
- Conditions
- Osteoarthritis
- Registration Number
- NCT00372801
- Lead Sponsor
- GlaxoSmithKline
- Brief Summary
To demonstrate that new drugs work, many complex multidose studies are often required. The intent of this study is to use Ibuprofen as an example of a marketed pain relief drug to validate a simpler single dose model for future assessment of new pain drugs.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 36
Inclusion Criteria
Not provided
Exclusion Criteria
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Primary Outcome Measures
Name Time Method Pain intensity recorded over 0-8 hours using question 1 of the WOMAC (Western Ontario and McMaster University Osteoarthritis Index)pain subscale (visual analog scale).
- Secondary Outcome Measures
Name Time Method Responder rate Patient impression of change - 8 & 24 hrs post dose Time to use of rescue medication (paracetamol)
Trial Locations
- Locations (1)
GSK Investigational Site
🇦🇺Randwick, Sydney, New South Wales, Australia