Comparison of emergence time between sevoflurane alone and short duration desflurane after sevoflurane in general anesthesia patients
- Conditions
- Not Applicable
- Registration Number
- KCT0006780
- Lead Sponsor
- Kosin University Gospel Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 70
1) Patients aged 18-65 years
2) Patients expected to undergo general anesthesia for more than 2 hours during elective surgery
3) Patients corresponding to American Society of Anesthesiologist Status 1-2
? American Society of Anesthesiologist Status 1: Normal healthy patient
? American Society of Anesthesiology Classification 2: Patients with mild systemic disease (mild systemic disease without functional impairment)
1) Patients under total intravenous anesthesia
2) Emergency surgery patients
2) body mass index = 30 kg/m2
3) Pregnant and lactating women
4) Patients with lung diseases such as asthma and COPD
5) Patients allergic to drugs (including inhaled anesthetics)
a. Patients with a history of hypersensitivity to sevoflurane, desflurane, or other halogenated anesthetics
b. Patients with a history of hypersensitivity to remifentanil and other fentanyl analogues
c. Patients with a history of hypersensitivity to rocuronium and any of its components or neuromuscular blockers
6) Patients with kidney disease (patients with creatinine clearance less than 60ml/min, patients with renal impairment with a baseline blood creatinine value of 1.5 mg/dL or more)
7) Patients with liver dysfunction
8) Patients with neuromuscular junction disease, including patients with myasthenia gravis and myasthenia gravis
10) Patients who have difficulty in voluntary consent;
11) Patients with a history of psychiatric disorders, including those with difficulty in normal communication
12) Past and family history of malignant hyperthermia
13) Patients with convulsions and patients with acute hepatic porphyria
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Time required to reach 80 bispectral index after discontinuation of inhaled anesthetic,;Time to open eyes: the time it takes for the patient to open their eyes after stopping the inhaled anesthetic according to a verbal command
- Secondary Outcome Measures
Name Time Method Time elapsed between discontinuation of inhalation anesthetic and removal of the endotracheal tube;side effects after general anesthesia, such as dizziness, nausea, and vomiting while entering the postanesthesia case unit