Comparison between intraarticular dexmedetomidine and morphine for postoperative analgesia after arthroscopic meniscal surgery

Phase 3

Completed

• Conditions: Postoperative analgesia; Arthroscopy; Anaesthesiology - Pain management; Surgery - Other surgery

• Registration Number: ACTRN12611000772943
• Lead Sponsor: King Abdulaziz University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2011-07-22
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 45

Inclusion Criteria

American Society of Anesthesiologists’ physical class I or II
- Arthroscopic meniscal surgery under general anaesthesia
- Elective surgery

Exclusion Criteria

- Regional anaesthesia
- History of opioids or sedative agents use on regular basis for more than a week prior to surgery
- renal impairment (serum creatinine > 200 mcg/ml)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Visual analogue scale (VAS) score (0-10) at rest[Before induction of anesthesia, on arrival to recovery room, and at 1, 2, 3, 4, 6, 8, 12, 18, 24, 30, 36, 42, and 48 hours after surgery];Visual analogue scale (VAS) score (0-10) on movement[Before induction of anesthesia, on arrival to recovery room, and at 1, 2, 3, 4, 6, 8, 12, 18, 24, 30, 36, 42, and 48 hours after surgery]

Secondary Outcome Measures

Name	Time	Method
Observers Assessment of Alertness and Sedation (OAA/S) score[Before induction of anesthesia, on arrival to recovery room, and at 1, 2, 3, 4, 6, 8, 12, 18, 24, 30, 36, 42, and 48 hours after surgery];Time to first analgesia request postoperatively (minutes)[Up to 48 hours postoperatively];Total amount of tramadol administered postoperatively[Up to 48 hours postoperatively]