Measuring Athlete's Risk of Cardiovascular events
Recruiting
- Conditions
- atherosclerosiscoronary artery disease1001108210003216
- Registration Number
- NL-OMON35520
- Lead Sponsor
- Meander Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 300
Inclusion Criteria
Male athletes aged 45 years or older age, asymptomatic for heart disease who undergo exercise testing as part of a sports medical evaluation, who are able to understand the study procedure and objectives
Exclusion Criteria
Known cardiovascular disease
Rhythm other than sinusrhythm
Pacemaker rhythm
Not able to hold breath for 25 sec.
Asthma/COPD and resting heart rate > 70/min after intravenous administration with beta blocker)
Iodine-allergy
Hypertension (Blood pressure > 200/110 mmHg)
Obesity BMI >40 kg/m2
Decreased renal function (GFR <60 mL/min)
Language barrier
Unwillingness to be informed about possible incedental findings at CT-scan
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>- Risk of CV events determined with SCORE.<br /><br>- MDCT-cardiac imaging data: calcium score (Agatston, volume, mass), presence<br /><br>and severity of coronary artery disease, Total coronary atherosclerotic burden. </p><br>
- Secondary Outcome Measures
Name Time Method <p>- Life time physical activity<br /><br>- Incidental findings on MDCT scanning<br /><br>- Safety (in particular radiation exposure) and tolerability of MDCT scanning.</p><br>