Dynamic and Static Autoregulation After Brain Injury

Completed

• Conditions: Acute Brain Injuries; TBI (Traumatic Brain Injury); Intracranial Hemorrhages
• Interventions: Other: There are no interventions in this study

• Registration Number: NCT01069250
• Lead Sponsor: Johannes Gutenberg University Mainz

Brief Summary

The aim of the study assesses static and dynamic cerebrovascular autoregulation daily over one week in patients with traumatic brain injury or intracranial hemorrhage to quantify the temporal profile of the autoregulatory status.

Detailed Description

Not available

Study Timeline

• Study Start: 2001-08
• Primary Completion: 2009-12
• Study Completion: 2010-02
• Study First Submitted: 2010-02-16
• Study First Submitted QC: 2010-02-16
• Study First Posted: 2010-02-17
• Status Verified: 2013-08
• Last Update Submitted: 2013-08-21
• Last Update Posted: 2013-08-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 16

Inclusion Criteria

• Traumatic brain injury
• Intracranial hemorrhage

Exclusion Criteria

• Measurement of TCD were impossible
• Injury of the legs (if the both tigh cuffs for dynamic autoregulation could not be fixed)

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Brain injury	There are no interventions in this study	Patients after traumatic brain injury or spontaneous intracranial bleeding

Primary Outcome Measures

Name	Time	Method
Disturbed cerebrovascular autoregulation after brain injury	7 days

Trial Locations

Locations (1)

University Medical Center of the Johannes Gutenberg-University Mainz; 🇩🇪 Mainz, Germany