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Risk Factors and Impact of Anesthesia Techniques on Myocardial Infarction Following Transurethral Resection of the Prostate

Completed
Conditions
Myocardial Infarction
Anesthesia
Transurethral Resection of Prostate Syndrome
Interventions
Other: general anesthesia or neuraxial anesthesia
Registration Number
NCT04047329
Lead Sponsor
Chang Gung Memorial Hospital
Brief Summary

This study examined the risk factors and the influence of the type of anesthetic used during transurethral resection of the prostate (TURP) on subsequent incidence of myocardial infarction (MI).

Detailed Description

This study utilized a population-based, nationwide dataset to evaluate the risk factors of MI for patients with benign prostate hypertrophy (BPH) who received TURP. Besides, The study also compared the different effects of general anesthesia (GA) and neuraxial anesthesia (NA) on the incidence of MI within 6 and 12 months after TURP.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
115025
Inclusion Criteria
  • Patients receiving TURP surgery (1998-2012)
Exclusion Criteria
  • Patients without anesthesia records
  • Patients receiving both general and neuraxial anesthesia
  • Mortality within 12 months of TURP

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Without post-operative myocardial infarctiongeneral anesthesia or neuraxial anesthesiaPatients without post-operative myocardial infarction after first admission for transurethral resection of the prostate
With post-operative myocardial infarctiongeneral anesthesia or neuraxial anesthesiaPatients with post-operative myocardial infarction after first admission for transurethral resection of the prostate
Primary Outcome Measures
NameTimeMethod
Patient's age (year-old) that developed post-TURP myocardial infarctionwithin 12 months after the first admission for TURP

We analyze age distribution of patients with post-TURP myocardial infarction

Number of patients with pre-operative diagnosed heart disease history developing post-TURP myocardial infarctionwithin 12 months after the first admission for TURP

We analyze pre-operative diagnosed heart disease rate in patients who had myocardial infarction after the surgery of TURP.

Number of patients with pre-operative diagnosed hypertension developing post-TURP myocardial infarctionwithin 12 months after the first admission for TURP

We analyze pre-operative diagnosed hypertension rate in patients who had myocardial infarction after the surgery of TURP.

Number of patients with pre-operative diagnosed stroke history developing post-TURP myocardial infarctionwithin 12 months after the first admission for TURP

We analyze pre-operative diagnosed stroke rate in patients who had myocardial infarction after the surgery of TURP.

Postoperative myocardial infarctionwithin 12 months after the first admission for TURP

Patients experienced myocardial infarction after transurethral resection of the prostate (TURP)

Number of patients with pre-operative diagnosed gout developing post-TURP myocardial infarctionwithin 12 months after the first admission for TURP

We analyze pre-operative diagnosed gout rate in patients who had myocardial infarction after the surgery of TURP.

Number of patients with pre-operative diagnosed liver cirrhosis history developing post-TURP myocardial infarctionwithin 12 months after the first admission for TURP

We analyze pre-operative diagnosed liver cirrhosis rate in patients who had myocardial infarction after the surgery of TURP.

Number of patients with pre-operative diagnosed chronic obstructive pulmonary disease developing post-TURP myocardial infarctionwithin 12 months after the first admission for TURP

We analyze pre-operative diagnosed chronic obstructive pulmonary disease rate in patients who had myocardial infarction after the surgery of TURP.

Number of patients with pre-operative diagnosed Diabetes Mellitus developing post-TURP myocardial infarctionwithin 12 months after the first admission for TURP

We analyze pre-operative diagnosed Diabetes Mellitus rate in patients who had myocardial infarction after the surgery of TURP.

Number of patients with pre-operative diagnosed disorders of lipoid metabolism developing post-TURP myocardial infarctionwithin 12 months after the first admission for TURP

We analyze pre-operative diagnosed disorders of lipoid metabolism rate in patients who had myocardial infarction after the surgery of TURP.

Number of patients with pre-operative diagnosed asthma developing post-TURP myocardial infarctionwithin 12 months after the first admission for TURP

We analyze pre-operative diagnosed asthma rate in patients who had myocardial infarction after the surgery of TURP.

Secondary Outcome Measures
NameTimeMethod
Number of patients who did not have post-operative myocardial infarction after receiving general anesthesia for TURPwithin 12 months after the first admission for TURP

Number of patients who did not have post-operative myocardial infarction after receiving general anesthesia for TURP

Number of patients who had post-operative myocardial infarction after receiving general anesthesia for TURPwithin 6 months after the first admission for TURP

Number of patients who had post-operative myocardial infarction after receiving general anesthesia for TURP

Number of patients who had post-operative myocardial infarction after receiving neuraxial anesthesia for TURPwithin 6 months after the first admission for TURP

Number of patients who had post-operative myocardial infarction after receiving neuraxial anesthesia for TURP

Number of patients who did not have post-operative myocardial infarction after receiving neuraxial anesthesia for TURPwithin 12 months after the first admission for TURP

Number of patients who did not have post-operative myocardial infarction after receiving neuraxial anesthesia for TURP

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