Improving Attention in Individuals With Long COVID-19
- Conditions
- Long Covid
- Interventions
- Other: Music GroupOther: Attention Training
- Registration Number
- NCT06503874
- Lead Sponsor
- Shirley Ryan AbilityLab
- Brief Summary
This study is to find out if the Attention Processing Training program is a potential treatment for brain fog symptoms, reported by people with Long-Covid. Also investigating the feasibility of completing this program virtually.
- Detailed Description
The goal of this project is to test the feasibility, acceptability and efficacy of an attention training intervention (Attention Process Training; APT-3) as a potential treatment for brain fog symptoms experienced by people with Long-Covid. There already is good empirical evidence to support the idea that the APT-3 treatment is feasible and effective in improving attention in people with acquired brain injuries, but information about its efficacy and acceptability in people with Long-Covid brain fog is lacking.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 60
- Aged 18-65 years.
- A history of confirmed SARS-CoV-2 infection.
- Subjective reports of cognitive symptoms that interfere with everyday activities, starting on or shortly after SARS-CoV-2 infection.
- Continuation or development of Long-Covid brain fog 3 months after the initial SARS-CoV-2 infection, with these symptoms lasting for at least 2 months with no other explanation.
- Objective attentional deficits as measured by the Conners CPT-312, and/or the Digit Span subtest (WAIS- III13).
- Able to use a keyboard.
- Able to understand and communicate in English.
- Able to consent independently.
- Being hospitalized due to COVID-19 diagnosis for more than 3 days.
- Pre-morbid neurological conditions that could potentially affect cognition, such as Parkinson's Disease, Alzheimer's Dementia, acquired brain injury.
- Severe depression.
- Currently enrolled in cognitive training or physical exercise training.
- Receiving chemotherapy or radiation within last 6 months.
- Active substance abuse.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Music Program Music Group This group will receive an enhanced music experience. They will listen to pre determined music for 30 minutes per day, 5 days a week, for 4 weeks (10 hours total over 4 weeks). This will be delivered in a hybrid model that will combine, in person, remote, and independent sessions, similar to the Attention Training group. Once they complete the music program, they will have the option to complete the Attention Training. Attention Training Attention Training The computer based APT-3 intervention will be delivered in a hybrid model that will combine in-person therapy sessions at Shirley Ryan AbilityLab and practice sessions which will be completed remotely. The dosing of each intervention training will be 30 minutes per day, 5 days a week, for 4 weeks (10 hours total over 4 weeks). The difficulty of the tasks in both interventions will increase progressively as the participants improve in their skills. APT-3 treatment will be administered by a trained and certified speech-language pathologist.
- Primary Outcome Measures
Name Time Method Number of participants who successfully completed at least 80% of the study tasks sessions 2 years Recording the number of participants who completed at least 80% of the study sessions out of the number of all participants who enrolled in the study.
- Secondary Outcome Measures
Name Time Method Change of scores in objective attention tests (i.e, CPT 3), pre- and post -intervention 2 year The Conners Continuous Performance Test Third Edition™ (Conners CPT 3™)
Trial Locations
- Locations (1)
Shirley Ryan AbilityLab
🇺🇸Chicago, Illinois, United States