Comparison of pain relieving efficacy of Dexmedetomidine, Fentanyl and Dexamethasone as an adjuvant to Ropivacaine in above the Collar bone Brachial plexus block (USG guided) when administered perineurally in adult patients undergoing upper limb surgery .

Phase 4

Not yet recruiting

• Conditions: Medical and Surgical,

• Registration Number: CTRI/2020/08/027358
• Lead Sponsor: Dr Sampurnanand Medical College Jodhpur

Brief Summary

We will compare the efficacy of ropivacaine and three other adjuvants drugs in ultrasound guided supraclavicular brachial plexus block in upper limp orthopaedic surgeries.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-08-24
• Last Update Posted: 2020-08-24

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

All patients aged 20 to 60 years of either gender of ASA physical statue I and II undergoing upper limb surgery who willing to participate in the study.

Exclusion Criteria

• 1.Patient refusal, 2.Hypersensitivity to amide local anaesthetics according to past history 3.Hypersensitivity to fentanyl, dexamethasone, dexmedatomidine infection at the injection site 4.
• Pregnant woman ( Urine Pregnancy Test positive) 5.Obesity (BMI >30kg/m2 ) 6.
• Uncooperative patients 7.
• Anatomical abnormality at the site of injection 8.Bleeding disorders ( Deranged PT-INR , Clotting time and Bleeding time) 9.Peripheral neuropathy or neurological deficit ( Based on history of neurological disease and Clinical Neurological assessment- Fine Touch, Pin Test, Motor power) 10.
• Concurrent chronic analgesic therapy 11.
• Known hepatic or renal insufficiency( Deranged LFT, SGOT, SGPT, Serum Creatinine, Blood Urea) 12.Field block1.Patient refusal, 2.Hypersensitivity to amide local anaesthetics according to past history 3.Hypersensitivity to fentanyl, dexamethasone, dexmedatomidine infection at the injection site 4.
• Known hepatic or renal insufficiency( Deranged LFT, SGOT, SGPT, Serum Creatinine, Blood Urea) 12.Field block failure.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the duration of analgesia produced in all three groups.	VAS Score analysis,blood pressure and heart rate before the procedure ,at the time of procedure and then every five minutes after the procedure.

Secondary Outcome Measures

Name	Time	Method
1) Onset of sensory block in minutes after the completion of block	2)Onset of motor block in minutes after the completion of block

Trial Locations

Locations (1)

MDM Hospital, Dr Sampurnanand medical college jodhpur; 🇮🇳 Jodhpur, RAJASTHAN, India

MDM Hospital, Dr Sampurnanand medical college jodhpur

🇮🇳Jodhpur, RAJASTHAN, India

Pradeep kumar Mulewa

Principal investigator

08005657338

Pradeepmulewa@gmail.com