Effects of Exercise on Energy Intake-Prescription of Resistance Exercise

Not Applicable

Completed

• Conditions: Eating Behavior; Food Reward
• Interventions: Other: medium inter-set rest; Other: medium inter-set rest with failure; Other: long inter-set rest; Other: short inter-set rest resistance exercise

• Registration Number: NCT06223282
• Lead Sponsor: National Taiwan Normal University

Brief Summary

Healthy young males will complete five trials in a randomized crossover counter-balanced order, including three different inter-set rest of resistance exercise in equal training volume, one repeated until failure and sedentary control. During each trial, blood samples will be collected.

The investigators hypothesized that different inter-set rest and training volume would affect subjective appetite and energy intake.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-10-28
• Primary Completion: 2023-03-31
• Study Completion: 2023-03-31
• Status Verified: 2024-01
• Study First Submitted: 2024-01-04
• Study First Submitted QC: 2024-01-15
• Last Update Submitted: 2024-01-15
• Study First Posted: 2024-01-25
• Last Update Posted: 2024-01-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 18

Inclusion Criteria

• Age: 20-30
• Healthy male

Exclusion Criteria

• No acute or chronic musculoskeletal symptoms
• Smoking
• Alcohol or drug abuse
• Failure to conduct resistance exercise

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
medium inter-set rest	medium inter-set rest	3 multi-joints resistance exercise with medium(120s) inter-set rest
medium inter-set rest with failure	medium inter-set rest with failure	3 multi-joints resistance exercise with medium (120s) inter-set rest repeated to failure each set
long inter-set rest	long inter-set rest	3 multi-joints resistance exercise with long (180s) inter-set rest
short inter-set rest	short inter-set rest resistance exercise	3 multi-joints resistance exercise with short (60s) inter-set rest

Primary Outcome Measures

Name	Time	Method
Subjective appetite	4-hour during each study intervention	The appetite perceptions were obtained through a 0-100 mm visual analog scale. The variables assessed included perceptions of hunger (i.e., "How hungry do you feel?"), satisfaction (i.e., "How satisfied do you feel?"), fullness (i.e., "How full do you feel?"), prospective food consumption (i.e., "How much do you think you can eat?"), and nausea (i.e., "How nauseous do you feel?"), with 0 indicating "not at all" and 100 signifying "extremely.".
Change in active-GLP-1	4-hour during each study intervention	active-GLP-1 in pg/mL
Change in lactate	4-hour during each study intervention	insulin in mmol/L
Change in acyl-Ghrelin	4-hour during each study intervention	acyl-Ghrelin in pg/mL
Change in total-Ghrelin	4-hour during each study intervention	total-Ghrelin in pg/mL
Change in PYY	4-hour during each study intervention	PYY in pg/mL
Change in total-GLP-1	4-hour during each study intervention	total-GLP-1 in pg/mL

Secondary Outcome Measures

Name	Time	Method
Taste appeal bias	4 hours during each study intervention	Taste preference (savoury or sweet) was calculated by subtracting the mean savory scores from the mean sweet scores. Positive values suggest a preference for sweet foods, while negative scores indicate a preference for savory foods, and a score of 0 signifies an equal preference between taste categories.
Change in insulin	4 hours during each study intervention	insulin in mU/L
Energy intake	3 days during each study intervention	Participants are required to record their diet for the day before, the current day, and the day following the experiment.
Change in TG	4 hours during each study intervention	TG in mg/dL
Implicit wanting	4 hours during each study intervention	Participants were given a set of food image pairs and were asked to select their preference by answering the question, "Which food do you desire the most at the moment?". The implicit wanting calculation involved further consideration of response time data based on preference choices using a standardized equation.
Relative preference	4 hours during each study intervention	Participants were given a set of food image pairs and were asked to select their preference by answering the question, "Which food do you desire the most at the moment?". The relative preference was the sum of the times each type of food was chosen, with a maximum value of 48 and a minimum value of 0.
Change in glucose	4 hours during each study intervention	glucose in mg/dL
Explicit liking	4 hours during each study intervention	A visual analog scale ranging from 0 to 100 mm was utilized to evaluate the question, "How pleasant would it be to taste some of this food now?" with 0 indicating "not at all" and 100 signifying "extremely."
Explicit wanting	4 hours during each study intervention	A visual analog scale ranging from 0 to 100 mm was utilized to evaluate the question, "How much do you want some of this food now?" with 0 indicating "not at all" and 100 signifying "extremely."
Fat appeal bias	4 hours during each study intervention	Fat preference (high or low) was calculated by subtracting the mean low-fat scores from the mean high-fat scores. Positive values suggest a preference for high-fat foods, while negative scores indicate a preference for low-fat or savory foods, and a score of 0 signifies an equal preference between fat content.

Trial Locations

Locations (1)

National Taiwan Normal University; 🇨🇳 Taipei, Taiwan