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A Study of 25-hydroxy Vitamin d Levels in Non-itching Hemodialysis Patients

Completed
Conditions
Vitamin D Deficiency
End Stage Renal Disease
Registration Number
NCT01548716
Lead Sponsor
Winthrop University Hospital
Brief Summary

Hypothesis:

25-hydroxy vitamin D levels in non-itching hemodialysis (HD) patients will be higher than those in HD patients with itching

25-hydroxy vitamin D levels will be measured in non-itching hemodialysis patients and compared to levels previously measured in a previous study of 25-hydroxy vitamin D levels of patients complaining of itching.

Detailed Description

25-hydroxy vitamin D levels from non-itching HD patients in this study will be compared to 25-hydroxy vitamin D levels from our ongoing study in HD patients with itching. The primary endpoints for both studies are continuous variables. Student's t test will be used to test for statistical significance. Multiple regression analysis will be used for controlling covariates and testing the interaction among covariates.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
50
Inclusion Criteria
  • Hemodialysis treatment for > 3 months No complaints of itching within 1 month prior to study enrollment
Exclusion Criteria
  • Age < 18 years
  • Failure to provide informed consent
  • Intact PTH < 70 pg/ml or > 1,000 pg/ml
  • Serum phosphorus > 7.0
  • Serum calcium (adjusted for albumin)> 11
  • Active malignancy
  • Likelihood of imminent renal transplantation
  • Current ergocalciferol treatment

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
25 hydroxy vitamin D levelup to 2 weeks

Pt will have blood sample taken and fill out 1) Pruritis Survey 2) Phosphorus Restriction Compliance Survey

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (2)

Winthrop University Hospital

🇺🇸

Mineola, New York, United States

Winthrop University Hospital Dialysis Unit

🇺🇸

Mineola, New York, United States

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