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临床试验/NCT01414023
NCT01414023已完成不适用

Assessing the Effects of a Neurobehavioral Intervention on Symptoms of Obsessive Compulsive Disorder

Boston University Charles River Campus2 个研究点 分布在 1 个国家目标入组 48 人开始时间: 2011年7月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
48
试验地点
2
主要终点
OCI-R scores

研究概览

简要总结

This experiment will examine if the use of computerized tasks that train individuals to control their attention more effectively will predict individual differences in obsessive-compulsive symptoms, rumination and BDNF change. After giving consent, filling out self-report forms, and giving blood for the BDNF test, 80 participants will be randomized to Cognitive Control Training (CCT) or Peripheral Vision Task (PVT) (described below) which will be administered three times over a two week period. At the third visit, participants will also complete an anagram task and repeat the blood draw for BDNF testing. The investigators hypothesize that computerized tasks that train individuals to control their attention more effectively will reduce Obsessive Compulsive (OC) symptoms. Additionally, individuals training in CCT will show increased ability to disengage from unattainable goals as assessed by responses to an unsolvable anagram task. Finally, individuals training in CCT will show a greater increase in BDNF levels as compared to individuals training in PVT.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Single Group
主要目的
Treatment
盲法
Single (Participant)

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Adults ages 18-65 years
  • OCI-R total score ≥ 16
  • Ability to read and provide informed consent.
  • Familiarity with a computer keyboard and mouse.

排除标准

  • BDI-II suicidality score of > 1

结局指标

主要结局

OCI-R scores

时间窗: up to two weeks

3 times over a two week period

次要结局

  • BDNF serum levels(up to two weeks)

研究者

发起方
Boston University Charles River Campus
申办方类型
Other
责任方
Sponsor

研究点 (2)

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