Use of a Novel Neuroplasticity-based Neurobehavioral Intervention for PTSD

Not Applicable

Completed

• Conditions: Anxiety; Depression

• Registration Number: NCT01694316
• Lead Sponsor: Stanford University

Brief Summary

The present study will explore the effectiveness of a computer based neurobehavioral intervention in alleviating symptoms and improving emotion regulation in individuals with PTSD. It will increase understanding of psychopathology at a neural-circuit level and aid development of new non-pharmacological treatment for PTSD. The study is managed by the Etkin Lab at Stanford University in California, but participants from the entire US are welcome to participate as the study is delivered online.

Detailed Description

Not available

Study Timeline

• Study Start: 2012-09
• Study First Submitted: 2012-09-24
• Study First Submitted QC: 2012-09-26
• Study First Posted: 2012-09-27
• Primary Completion: 2017-01
• Study Completion: 2017-01
• Status Verified: 2018-08
• Last Update Submitted: 2018-08-14
• Last Update Posted: 2018-08-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 54

Inclusion Criteria

• current PTSD
• internet access

Exclusion Criteria

• lifetime psychotic disorder,
• past-year substance dependence

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
WebNeuro Computerized Cognitive and Affective Assessment Battery	Baseline and 3-month	Age and gender-normed Z scores for the following measures: Sustained attention accuracy, Sustained attention lapses, Sustained attention false alarms, Working memory capacity, Visual scanning speed, Inhibition executive control, Processing speed, Maze completion executive control accuracy, Maze completion executive control speed, Immediate verbal memory, Delayed verbal memory, Inhibitory motor control accuracy, Inhibitory motor control lapses, Facial affect identification accuracy (happy, fearful, angry, sad, and disgusted), Facial affect identification speed (happy, angry, fearful, sad, or disgusted), Facial affect identity recognition accuracy (happy, angry, sad, fearful, or disgusted), Facial affect identity recognition speed (happy, sad, angry, fearful, or disgusted), Emotional conflict reaction time slowdown, Regulation of emotional conflict reaction time slowdown

Secondary Outcome Measures

Name	Time	Method
Clinician-assessed PTSD symptoms	Baseline and 3-month	Total and symptom sub scale scores from the Clinician-Administered PTSD Scale for DSM-IV (CAPS)

Trial Locations

Locations (1)

Stanford University, Department of Psychiatry and Behavioral Sciences; 🇺🇸 Stanford, California, United States