MedPath

Neuroplasticity-oriented Cognitive Intervention in Early Onset and First Admission Schizophrenia

Not Applicable
Completed
Conditions
Psychosis
Interventions
Behavioral: Brain Fitness Training, Posit Science SF
Registration Number
NCT01781364
Lead Sponsor
University of Konstanz
Brief Summary

The purpose of this study is to reveal the specific effects of computer-aided cognitive training on course and rehabilitation in early onset schizophrenia

Detailed Description

Impairment in cognitive functions is one of the main symptoms in schizophrenia and is currently one of the challenges in the treatment of the disease. We examine the beneficial effect of computer-aided training program on course and rehabilitation of young psychotic patients with early onset psychosis. In addition we develop predictors for the course of disorder from neuroimaging data.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
20
Inclusion Criteria
  • Early Onset Psychosis
Exclusion Criteria
  • Chronicity
  • Insufficient German skills

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Cognitive TrainingBrain Fitness Training, Posit Science SFBrain Fitness Training, Posit Science SF
Primary Outcome Measures
NameTimeMethod
change from baseline at post-training and at 3-months and at 7-months follow-up in each of the following outcome measures: neuropsychological test performance (MCCCB), GAF, PANSS, MEG event-related potentials (M50), alpha activitybaseline, post-training (training duration 4 weeks), 3-month follow-up, 7-month follow-up
Secondary Outcome Measures
NameTimeMethod
change from baseline in GAF score at 3-months and 7-moths follow-upbaseline, 3-months follow-up, 7-months follow-up

Trial Locations

Locations (1)

University Konstanz

🇩🇪

Konstanz, Baden Wuerttemberg, Germany

University Konstanz
🇩🇪Konstanz, Baden Wuerttemberg, Germany
© Copyright 2025. All Rights Reserved by MedPath