To compare sugammadex and neostigmine to acess hemodynamic response during the recovery of rocuronium in the brain surgery
Not Applicable
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2024/07/070154
- Lead Sponsor
- DR KIRTI VERMA
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
All pateints age group 18-65years with craniotomy surgeries and giving written informed consent.
ASA GRADE 1 TO 3.
Exclusion Criteria
1.Pateint refuse to participate.
2.Renal,Hepatic,Ventilatory Dysfunction.
3.Increased intracranial pressure.
4.Pregnancy or lactation.
5.Pateints with muscular dystrophies,myopathy,or cerebral palsy.
6.Pateints with a history of intolerance to any of the study drugs.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the hemodynamic response Heart rate,SBP,DBP,MAP,SPO2 of sugammadex versus Neostigmine in reversal of rocuronium in pateints undergoing craniotomy surgery.Timepoint: 2min,5min,10min,15min,30min,60min,2hr,6hr,12hr,18hr,24hr.
- Secondary Outcome Measures
Name Time Method 1.To evaluate the side effects (PONV) of sugammadex versus neostigmine in reversal of rocuronium in pateints undergoing craniotomy surgery. <br/ ><br>2.To evaluate the Train of four Response of sugammadex versus neostigmine in reversal of rocuronium in pateints undergoing craniotomy surgery.Timepoint: 2min,5min,10min,15min,30min,60min,2hr,6hr,12hr,18hr,24hr. <br/ ><br>