Interaction of coagulation FACtors, Thrombocytes and leukOcytes in patients with aRterial hypeRtension study
- Conditions
- I10Essential (primary) hypertension
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 71
Inclusion Criteria
essential arterial hypertension
Exclusion Criteria
Age =90 years, anticoagulant therapy (unfractionated or low molecular weight heparin, vitamin K antagonist, FXa-inhibitors, thrombin inhibitors), acute coronary syndromes, exacerbated disease requiring critical care medicine (e.g. hypertensive crisis with pulmonary edema and respiratory failure) or immediate surgery (e.g., aortic dissection or rupture).
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Correlation of the severity of arterial hypertension with markers of activation of the coagulation system as well as thrombocyte and leukocyte (patho)physiology. Medical history was taken and body weight, height and heart rate were obtained. Office blood pressure was measured in each study participant in an upright sitting position (room temperature 22° centigrade) using the Omron 705CP-II (Omron) device and upper arm cuffs adapted to upper arm circumference (17-22 cm, 22-32 cm an 32-42 cm, respectively). Immediately after that, a maximum of 10ml of venous citrated blood was drawn from the cubital vein of the right arm to prepare platelet rich and platelet poor plasma, leukocyte preparations and to assess blood count.
- Secondary Outcome Measures
Name Time Method