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Clinical Trials/NCT00913068
NCT00913068
Completed
Not Applicable

Post Operative Analgesia Using the Transverse Abdominal Plan (TAP) Block in Patients Undergoing a Radical Retropubic Prostatectomy (RRP)

Nova Scotia Health Authority1 site in 1 country110 target enrollmentJuly 2009
ConditionsProstate Cancer

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Prostate Cancer
Sponsor
Nova Scotia Health Authority
Enrollment
110
Locations
1
Primary Endpoint
Total Milligrams of Opiates
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

The researchers propose to investigate a relatively new anesthetic procedure, in order to maximize patient comfort and minimize the use of narcotics after a radical prostatectomy.

Detailed Description

Our current post operative analgesic strategy involves a multi-modal approach, using local injectable anesthetic around the incision and systemic medications (i.e. non-steroidal anti-inflammatories, acetaminophen and break-through doses of opiates). As the amount of opiates used can be significant, we have to be aware of their inherent risks. Opiates have an excellent pain control profile, working peripherally by decreasing the amount of neurotransmitters released from neurons involving noxious stimuli, and also in their central processing. Some of the more common adverse reactions are reparatory depression, sedation, confusion, delirium, nausea, pruritis, constipation, hypotension and bradycardia. Often it is these resulting side effects that extend the length of in hospital rehabilitation, and decrease a patient's overall satisfaction. Thus we propose the use of a relatively new regional anesthetic technique be employed to further decrease the need for opiates in our prostatectomy patients' post-op course, while adequately controlling their pain.

Registry
clinicaltrials.gov
Start Date
July 2009
End Date
September 2011
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Male

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Ricardo Rendon

Dr

Nova Scotia Health Authority

Eligibility Criteria

Inclusion Criteria

  • prostate cancer for radical prostatectomy

Exclusion Criteria

  • chronic pain or opiate use

Outcomes

Primary Outcomes

Total Milligrams of Opiates

Time Frame: 2, 6,12, 24, 48 and 72 hours

mean number of milligrams used postoperatively

Study Sites (1)

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