Intra articular ozone injection combined with Compound Angelica sinensis + vitamin B12 under ultrasound in the treatment of knee osteoarthritis

Phase 4

• Conditions: knee osteoarthritis

• Registration Number: ITMCTR2200006860
• Lead Sponsor: The First Affiliated Hospital of Guangxi Medical University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 6 March 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

Patients who meet the clinical diagnostic criteria for knee osteoarthritis recommended by the American College of rheumatology:
(1) Knee pain on most days in the past month;
(2) Bouncing sound during joint movement;
(3) Knee stiffness < 30 minutes;
(4) Age > 38;
(5) Knee joint bone fat with bouncing sound;
(6) Bone fat without bouncing.
Knee osteoarthritis can be diagnosed when the patient has (1) pain, accompanied by (2), (3), (4), (2), (3), (5) or (6).

Exclusion Criteria

(1) Unable to cooperate with the assessment;
(2) Allergic to the drugs used;
(3) Emergency treatment is needed in case of emergency;
(4) Age = 38 years;
(5) Severe cardiopulmonary insufficiency;
(6) Severe hepatic and renal insufficiency.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
VAS;

Secondary Outcome Measures

Name	Time	Method
Walking distance, Insall knee joint efficacy;