Standard colonoscopy versus high-definition colonoscopy with/without I-scan functions in the detection of colorectal neoplasia: a randomized multicenter study

Recruiting

• Conditions: darmpoliep; voorstadium van dikke darmkanker; 10017934; 10017987; 10017998

• Registration Number: NL-OMON33382
• Lead Sponsor: maag-darm-leverziekten

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 984

Inclusion Criteria

patients (> 40 years old) undergoing diagnostic colonoscopy because of one of the following five indications: 1: abdominal complaints, 2: chronic diarrhea, 3: (family) history of adenomateous polyps or CRC, 4: rectal bloodloss and 5: iron deficiency anemia.

Exclusion Criteria

Previous extended colon surgery, inflammatory bowel disease (IBD), Hereditary polyposis syndromes, known gastrointestinal neoplasia before endoscopy (based on recent endoscopy or other imaging like CT)
Patients <40 years

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study parameter will be the adenoma detection rate in all four groups.<br /><br>Other end-points are: total number of polyps per patient, total number of flat<br /><br>lesions and time of procedure (withdrawal time). Patients are stratified to the<br /><br>treatment center.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Amount of small and flat lesions<br /><br>Missed lesions (assessed by questionaire after 60 months)</p><br>