Quality of life study of palonosetron and dexamethasone in chemonaive patinets with advanced colorectal cancer treated with moderateemetic chemotherapy
- Conditions
- advanced colorectal cancer recieving moterate emetic chemotherapy
- Registration Number
- JPRN-UMIN000007932
- Lead Sponsor
- Osaka City General Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 110
Not provided
1. Uncontrolled severe complication disease, such as ileus, idiopatic pulmomary fibrosis, daibetes, cardiac infarction, angina pectoris, renal failure, hepatic failure, mental disorder, cerebral vansular disease, active gastrointestinal tract ulcer. 2. Symptomatic brain metastasis 3. Epilepsy patint treated with antiepileptic agent, exclusing being stable clinically 4. Patient with massive pleural effusion or ascitis to be required dranage 5. Obstruction of the gastric outlet or ileus 6.Grade 2 or more nausea and vomiting 7.Anaphylaxis to palonosetron or dexamethasone 8. Patients treated with 5-HT3 antagonist, NK1 antagonist, SSRI, SNRI 9.Patient not to use birth contorol 10. Unsuitable patients by investigator
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method