eurobiological and psychobiological signatures of vocal effort in early career teachers

Not Applicable

Recruiting

• Conditions: R49; Voice disturbances

• Registration Number: DRKS00030171
• Lead Sponsor: niversitätsklinikum Bonn

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-09-06
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 100

Inclusion Criteria

Teachers (max. 10 years full-time) or student teachers in good health between 21 and 39 years with symptoms of vocal fatigue.

Control participants in good health between 21 and 39 years without symptoms of vocal fatigue.

Exclusion Criteria

• Lefthandedness
• Smoking (past 5 years)
• Known changes of the vocal folds (e.g., vocal fold nodules), vocal fold paralysis, surgeries on the larynx or thryoid or current organic or neurological changes of the vocal folds or vocal function per videoendoscopy and -stroboscopy of the larynx
• History of voice therapy
• Hoarseness
• Respiratory illness, allergies (respiratory, silver), reflux or asthma at time of participation
• Hearing disorder or hearing aids
• Psychological, neurological or endocrinological disorders
• Psychotropic or steorid medications
• Body mass index > 30
• Indications against MRI such as metail parts in or on the body (e.g., permanent dental prostheses or braces, screws, prostheses, piercings or large tattoos
• Nearsightedness > -5 diopters, if only glasses are worn
• Claustrophobia
• Pregnancy

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Vocal fatigue (raw scores, Vocal Fatigue Index, VFI Factor 1, Experiment 1 & 2)<br>MRI activation in regions of interest (BOLD area 4p in mean %) as a function of speech tasks with and without stress induction (Experiment 1)<br>Salivary cortisol (nmol/L) to determine stressresponders and nonresponders (Experiment 1)<br>Suprahyoid and infrahyoid muscle activity (RMS, Experiment 1 & 2)<br>Personality trait Social Potency (T-scores, Multidimensional Personality Questionnaire, MPQ, Experiment 1)<br>Personality trait Stress Reaction (T-scores, Multidimensional Personality Questionnaire, MPQ, Experiment 1)<br>Personality social anxiety (T-scores, Liebowitz Social Anxiety Scale, LSAS-fear, Experiment 1)