Efficacy and safety of a traditional Chinese medicine yokukansan for chorea and psychosis in the Huntington's disease.

Phase 2

• Conditions: Huntington' s disease

• Registration Number: JPRN-UMIN000001659
• Lead Sponsor: Dept. Nerol and Center for traditional Asian medicine, Tohoku University Graduate school of medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2009-08-01
• Study Completion: 2010-05-01
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

Not provided

Exclusion Criteria

1.With any malignancy 2.With severe heart disease, liver disease, blood disease, respiratory disease and any other severe diseases influenced on the patients states 3.With any neurodegenerating diseases other than Huntington's disease 4.Alcohol abuse, drug abuse, metabolic toxicity, chronic inflammatory diseases 5.Who can not take the herbal medicine. 6.Who are perscribed any antipsychotics newly in the observation period. 7.Others who are judged as inadequate by attending doctors.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
nified Huntington's Disease Rating Scale (UHDRS) Neuropsychiatric Inventry(NPI)

Secondary Outcome Measures

Name	Time	Method
Cognitive function, ADL, Use of rescue drug, toralance