The effect of L/N type Calcium channel blocker on blood pressure variability in elderly hypertensive patients
Not Applicable
Recruiting
- Conditions
- Hypertension
- Registration Number
- JPRN-UMIN000014843
- Lead Sponsor
- Osaka university graduate school of medicine The department of geriatric medicine and nephrology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Not provided
Exclusion Criteria
1.Secondary hypertension, malignant hypertension 2.Stroke or myocardial infarction during 6months 3.Coronary intervention during 6months 4.Congestive heart failure with NYHA class III or more 5.Aortic stenosis 6.Arterial fibrillation, arterial flutter or malignant arrhythmia 7.Severe hepatic injury 8.Sensitivity to trial drug 9.Excluded by physicians decision
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method (Comparison among step1, step2, and step3) Home BP variability (interdaily variability, intradaily variability (morning, night) BP variability during sleep Home pulse rate variability (interdaily variability, intradaily variability (morning, night) pulse rate variability during sleep
- Secondary Outcome Measures
Name Time Method 1.BP and pulse rate at outpatient (average of two measurements) 2.Index of oxidative stress 3.Renal function (Ualb/Cr. eGFR) 4.Sympathetic nerve activity