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Effect of T/L-type calcium channel blockers on serum biomarkers for cardiovascular functio

Not Applicable
Conditions
Hypertension
Registration Number
JPRN-UMIN000008325
Lead Sponsor
Division of Cardiovascular Medicine, Kobe University Graduate School of Medicine
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
60
Inclusion Criteria

Not provided

Exclusion Criteria

Patients with severe uncontrolled hypertension (diastolic BP over 110 mmHg), secondary hypertension, hyperuricemia, a past history of gout attack, poorly controlled [glycated hemoglobin A1c (HbA1C over 8.0] or insulin-treated diabetes mellitus, cardiovascular events including myocardial infarction and stroke within the preceding 3 months, severe liver dysfunction, renal failure (serum creatinine over 2.0 mg/dL), active malignancy, pregnancy, severe bile dysfunction, or allergy to benidipine or amlogipin were excluded from the study.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
blood pressure, serum lipid profile, electrites, endocrinological profile
Secondary Outcome Measures
NameTimeMethod
left ventricular mass, cardiovascular function
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