Effect of T/L-type calcium channel blockers on serum biomarkers for cardiovascular functio
- Conditions
- Hypertension
- Registration Number
- JPRN-UMIN000008325
- Lead Sponsor
- Division of Cardiovascular Medicine, Kobe University Graduate School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 60
Not provided
Patients with severe uncontrolled hypertension (diastolic BP over 110 mmHg), secondary hypertension, hyperuricemia, a past history of gout attack, poorly controlled [glycated hemoglobin A1c (HbA1C over 8.0] or insulin-treated diabetes mellitus, cardiovascular events including myocardial infarction and stroke within the preceding 3 months, severe liver dysfunction, renal failure (serum creatinine over 2.0 mg/dL), active malignancy, pregnancy, severe bile dysfunction, or allergy to benidipine or amlogipin were excluded from the study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method blood pressure, serum lipid profile, electrites, endocrinological profile
- Secondary Outcome Measures
Name Time Method left ventricular mass, cardiovascular function