Diagnosis of Ascites in Infants and Children
试验速览
- 阶段
- 不适用
- 入组人数
- 50
- 主要终点
- Diagnosis of ascites in infants and children with hepatic, cardiac, renal disease, tuberculosis and malignancy
研究概览
简要总结
Ascites is the pathologic accumulation of fluid within the peritoneal cavity. Causes of ascites in infants and children :hepatobiliary disorders,serositis, neoplasm, cardiac, genitourinary disorder, metabolic disease and others.
Diagnosis of ascites :history of abdominal distention, increasing weight, respiratory embarrassement, symptoms and signs of (hepatic ,cardiac,renal disease, tuberculosis and malignancy).
lnvestigation:complete blood count, complete urine examination, liver function tests, plasma proteins, renal function tests, clotting screen, tuberculin test, chest and abdominal plain films,abdominal ultrasound, upper gastrointestinal endoscopy, abdominal paracentesis for ascitic fluid analysis .
详细描述
Definition : Ascites is the pathologic fluid accumulation within the peritoneal cavity .
causes of ascites in infants and children :
- Hepatobiliary disorders (cirrhosis, congenital hepatic fibrosis, acute hepatitis B,C ,Budd -chiari syndrome, Bile duct perforation)
- Serositis (crohn's disease, eosinophilic enteropathy , Henoch- Shonlein purpura )
- Neoplasm (lymphoma, wilm's tumor ,Glioma, Germ cell tumor, Ovarian tumor,mesothelioma, Neroblastoma )
- Cardiac (Heart failure )
- Metabolic disease
- Gastrointestinal disorder (Nephrotic syndrome, peritoneal dialysis ). Diagnosis of ascites :History of abdominal distention, increasing weight, respiratory embarrassement, jaundice, bleeding (haematemsis, melena, and epistaxis ),Pruritus ,Growth failure ,abdominal pain, fever,Cyanosis, ,dyspnea during suckling, Orthopnea, Buffy eyes, lower limb swelling, Haematrruria .
By examination : Tachycardia ,Tachypnea ,Hypertension ,cyanosis, jaundice, clubbing of fingers ,limb edema ,Hepatomegaly, splenomegaly, dilated abdominal wall veins.
Investigations :
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 1 Month 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age from 1month to 18 year
- •infants and children with ascites (hepatic, cardiac, renal, malignant or tuberculous )
- •infants and children with peritonitis
排除标准
- •age <1month
- •surgical conditions as ruptured viscous or located abscess
结局指标
主要结局
Diagnosis of ascites in infants and children with hepatic, cardiac, renal disease, tuberculosis and malignancy
时间窗: 1 year
Diagnosis of ascites in infants and children fromega age of 1month to 18 year
次要结局
未报告次要终点
研究者
Asmaa abo bakr Ahmed
Doctor
Assiut University