Clinical study of rhubarb combined with percutaneous electrical stimulation to improve acute gastrointestinal injury in patients with sepsis

Phase 1

• Conditions: sepsis

• Registration Number: ITMCTR2100005286
• Lead Sponsor: Affiliated Hospital of Jiangsu University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

? Older than 18 and younger than 80 years old;
? Patients admitted to ICU;
? Meet the diagnostic criteria of sepsis 3.0;
? Meet AGI diagnostic criteria, and grade is I, II, III;
? Patients or their family members signed informed consent and cooperated with the investigation with good compliance.

Exclusion Criteria

? Gastrointestinal perforation, intestinal obstruction, gastrointestinal surgery, intestinal fistula and other contraindications of enteral nutrition
? Patients with skin infection, ulcers and scars are not suitable for acupoint electrical stimulation treatment
? AGI: level IV
? The patients are endangered and their expected survival time is less than 5 days
? Patients with impaired immune function or undergoing immunotherapy
? Pregnant women
? Are participating in other clinical trials
? Patients refused to participate in the study

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Time for enteral nutrition to reach standard;target-reach of EN at day 7;Regular bowel sounds recovery time;Antral motility index;

Secondary Outcome Measures

Name	Time	Method
Prognostic indicators;Intestinal mucosal permeability index;Infection index;Nutrition indicators;Gastrointestinal motility index;The immune indexes;Inflammation levels;