The effect of Ondansetron on postoperative delirium in elderly patients

Phase 3

• Conditions: Delirium.; Sedative, hypnotic or anxiolytic use, unspecified with withdrawal delirium; F13.931

• Registration Number: IRCT20170515033986N1
• Lead Sponsor: Oroumia University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 22 July 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Patients with age over 60 years
Patients with ASA I and ASA II
Patients candidate of hip and proximal femoral fracture surgery

Exclusion Criteria

Patients with a history of dementia, Alzheimer, Parkinson or other neurological disorders
Alcohol usage
Patients with a history of hearing and speech disorders
Patients with a history of receiving of anti-depression and sedatives drugs
Duration of surgery more than 3 hours

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Delirium. Timepoint: Recovery, 30 minutes, one hour, 6 hours, 8 hours and 24 hours after surgery. Method of measurement: 4- point scale.

Secondary Outcome Measures

Name	Time	Method
ausea. Timepoint: Recovery,30 minutes, one hour, 6 hours, 8 hours and 24 hours after surgery. Method of measurement: Clinical examination.;Vomoting. Timepoint: Recovery, 30 minutes, one hour, 6 hours, 8 hours and 24 hours after surgery. Method of measurement: Leakage of stomach contents.;Pruritus. Timepoint: Recovery, 30 minutes, one hour, 6 hours, 8 hours and 24 hours after surgery. Method of measurement: Clinical examination.;Shivering. Timepoint: Recovery, 30 minutes, one hour, 6 hours, 8 hours and 24 hours after surgery. Method of measurement: Clinical examination.