Prognostic prediction of head and neck squamous cell carcinomas with clinico-pathological parameters and Epidermal growth factor receptors expression status

Completed

• Conditions: Malignant neoplasms of lip, oral cavity and pharynx, Medically fit for surgery,

• Registration Number: CTRI/2018/05/014222
• Lead Sponsor: MOHAMMAD AKHEEL

Brief Summary

The main background of this research is to

1. To find the prognosis of patient based on clinico-pathological parameters. ( pTNM staging, histological differentiation of tumor, depth of tumor, tumor margins, lymphovascular invasion, perineural invasion, anatomic location)

2. To check whether EGFR as an independant prognostic marker in SCC

3. Association of EGFR expression status with clinico-pathological parameters.

Detailed Description

Not available

Study Timeline

• Study Start: 2017-05-08
• Study Completion: 2019-03-06
• Last Update Posted: 2021-11-27

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• 1.All patients with squamous cell carcinomas of oral cavity 2.
• Fungating/non-fungating tumor mass.

Exclusion Criteria

• 1.Any previous treatment(Surgery/chemo-radiation) 2.
• Sarcomas/melanomas/ basal cell carcinomas of head and neck.
• 3.Recurrence cases.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To find whether there is association of EGFR and clinico-pathological factors with prognosis	1 year
To find whether the model created helps us to find the prognosis	1 year

Secondary Outcome Measures

Name	Time	Method
To find prognosis of patients	2 year

Trial Locations

Locations (1)

GREATER KAILASH HOSPITAL; 🇮🇳 Indore, MADHYA PRADESH, India

GREATER KAILASH HOSPITAL

🇮🇳Indore, MADHYA PRADESH, India

DR MOHAMMAD AKHEEL

Principal investigator

9584284566

drakheelomfs@gmail.com