A Randomized Trial of the Effects of Exercise Training in Chagas Cardiomyopathy

Federal University of Minas Gerais1 site in 1 country37 target enrollmentMarch 2007

ConditionsChagas Disease Cardiomyopathy Exercise Training

Overview

Phase: Phase 4
Intervention: Not specified
Conditions: Chagas Disease
Sponsor: Federal University of Minas Gerais
Enrollment: 37
Locations: 1
Primary Endpoint: Health related quality of life
Status: Completed
Last Updated: 10 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The benefits of exercise training in heart failure are well established. Its effects, however, have not been evaluated in Chagas cardiomyopathy (ChC). The investigators hypothesis is that the exercise training may improve functional capacity, quality of life (QoL), and reduce brain natriuretic peptide (BNP) levels in patients with ChC.

Registry

clinicaltrials.gov

Start Date

March 2007

End Date

March 2009

Last Updated

10 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Federal University of Minas Gerais

Responsible Party

Principal Investigator

Antonio Luiz Pinho Ribeiro

Professor

Federal University of Minas Gerais

Eligibility Criteria

Inclusion Criteria

•Chronic Chagas dilated cardiomyopathy, defined by the echocardiography finding of a dilated left ventricle with moderate or severe impaired left ventricular systolic function (left ventricular ejection fraction ≤ 45%).
•To be clinically stable for at least 3 months
•To have sinus rhythm
•To be under standard medical therapy use at the time.