EUCTR2020-004178-23-FI
Active, not recruiting
Phase 1
ltrasound Guided Repeated Bilateral Transversus Thoracis Muscle Plane Block (TTP) via catheter and postoperative pain in Cardiac Surgery - TTPcat
Conditionscardiac disease necessitating surgery with sternotomyMedDRA version: 20.0Level: LLTClassification code 10046972Term: Valvular heart disease NOSSystem Organ Class: 100000004849MedDRA version: 20.0Level: LLTClassification code 10055218Term: Ischemic heart diseaseSystem Organ Class: 100000004849Therapeutic area: Diseases [C] - Cardiovascular Diseases [C14]
Overview
- Phase
- Phase 1
- Intervention
- Not specified
- Conditions
- cardiac disease necessitating surgery with sternotomy
- Sponsor
- Turku University Hospital
- Enrollment
- 120
- Status
- Active, not recruiting
- Last Updated
- 5 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\.18 \- 80 years of age
- •2\.Scheduled for open cardiac coronary arterial bypass graft (CABG) OR single heart valve surgery that require median sternotomy under general anesthesia
- •3\.Patients that are estimated to be weaned from mechanical ventilator not later than 8 h after surgery
- •4\.Patients that are capable of using the patient controlled analgesia device (PCA) after surgery
- •5\.Written informed consent
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1\.2 Adults (18\-64 years) yes
- •F.1\.2\.1 Number of subjects for this age range 120
- •F.1\.3 Elderly (\>\=65 years) no
Exclusion Criteria
- •1\.A previous history of intolerance to the study drug or related compounds and additives
- •2\.Redo surgery
- •3\.Combined CABG and heart valve surgery
- •4\.Endocarditis and/or mediastinitis
- •5\.Concomitant drug therapy with strong opioids or strong CYP3A4 or CYP2D6 inductor(s) or inhibitor(s) 2 weeks prior to study.
- •6\.Patients younger than 20 years or older than 80 years.
- •7\.Body weight \< 60 kg
- •8\.BMI \> 35, sleep apnoea, any other sleep disorder or condition that requires treatment with continuous positive airway pressure or automatic positive airway pressure device.
- •9\.Existing significant liver or kidney disease
- •10\.History of alcoholism, drug abuse, psychological or other emotional problems that are likely to invalidate informed consent
Outcomes
Primary Outcomes
Not specified
Similar Trials
Not yet recruiting
Phase 4
ltrasound guided injection in the anterior abdominal wall intermuscular plane for pain relief after laparascopic gall bladder surgery: Local anesthetic vs Local anesthetic plus dexamethasone.Health Condition 1: Z768- Persons encountering health services in other specified circumstancesCTRI/2019/05/019020Medica Superspecialty Hospital
Recruiting
Not Applicable
ltrasound guided pudendal nerve block versus conventional technique for elective perineal surgeriesSurgeryPeri operative analgesiaAnaesthesiaPACTR201608001613798Anesthesia department Faculty of medicine tanta university68
Not yet recruiting
Phase 1
The technique of ultrasound guided transversus abdominis plane block in the placement of peritoneal dialysis catheters.The patients with end-stage renal disease who will get peritoneal dialysis.transversus abdominis plane blockanalgesiaperitoneal dialysisTCTR20150421001Department of Nephrology,West China Hospital of Sichuan University4
Not yet recruiting
Not Applicable
Anaesthesia to suppress cough after surgeries of vocal cords done using laserCTRI/2022/01/039794All India Institute of Medical Sciences Patna
Completed
Not Applicable
us guided BSCPB for thyroid surgeryNutritional, Metabolic, EndocrineSurgerythyroid surgeryAnaesthesiaPACTR201611001879340Mansourah oncology center40