se of calcium to improve fertilisation in patients with previous poor fertilisation or failed fertilisation and in patients with poor sperm quality.
Not Applicable
- Conditions
- Infertile patientsReproductive Health and Childbirth - Fertility including in vitro fertilisation
- Registration Number
- ACTRN12612001225808
- Lead Sponsor
- PIVET Medical Centre
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
All participants will be patients of PIVET Medical Centre and under the clinical management of one or more of the Fertility Specialists who work at PIVET. No outside patients will be involved in this study. Eligible patients must have had previous complete failed fertilisation, reduced fertilisation (<50%) or have severe male factor infertility (Sperm concentration < 2 x 106 million/ml, Sperm motility < 5%
Strict criteria normal morphology < 4%). Patients with surgically collected sperm (epididymal collected sperm or testicular collected sperm) will also be included
Exclusion Criteria
Any patients that has had fertilisation rate of greater than 50% in a previous cycle will be excluded
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method % Clinical pregnancy rate. We have an internal data base that will calculate: the rate of number of clinical pregnancies (presence of a heartbeat at 7 week ultrasound scan)/ number of embryo transfers[1 year];% Fertilisation rate. We have an internal data base that will calculate: the number of two pronuclear oocytes/the number of oocytes injected with sperm[1 year]
- Secondary Outcome Measures
Name Time Method % Blastocyst rate:We have an internal data base that will calculate: Number of blastocysts formed on Day 5 and/or Day 6/the number of two pronuclear oocytes[1 year];% Live Birth: Number of live babies born/number of embryo transfers[1-2 years]