Effects of normobaric intermittent Hypoxia-Hyperoxia in persons with dementia

Not Applicable

• Conditions: F00; F01; F02; F03; Dementia in Alzheimer disease; Vascular dementia; Dementia in other diseases classified elsewhere; Unspecified dementia

• Registration Number: DRKS00025130
• Lead Sponsor: Otto-von-Guericke-Universität Magdeburg Fakultät für Humanwissenschaften Institut III: Sportwissenschaft Lehrstuhl Gesundheit und körperliche Aktivität

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-05-12
• Study Completion: 2021-08-22
• Results First Posted: 2022-03-26
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 38

Inclusion Criteria

Residents of a geriatric facility
- Acceptance of the procedure (mask breathing).
- Voluntary participation and signing of the informed consent

Exclusion Criteria

- Smoker
- Obisity
- Symptoms of severe dementia that limit participation in the study (low compliance of participants)
- Cardiovascular disease such as untreated hypertension, coronary artery disease with unstable angina pectoris (CCS 3-4), severe heart failure (NYHA III-IV), and arrhythmias
- Untreated or uncontrolled diabetes mellitus
- Pulmonary fibrosis
- Cancer
- Acute inflammatory diseases
- Need for continuous or intermittent ventilation and/or oxygenation
- Arterial oxygen saturation at rest of less than 93%.
- simultaneously participation in other interventions

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Changes in global cognitive function via Dementia-Detection-Test (Pre-Test: within one week before Intervention, Post-Test: within one week after Intervention)