Types of Photoplethysmographic Waves in Adult Patients with Septic Shock
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 116
- 试验地点
- 1
- 主要终点
- Photoplethysmography wave types in adult patiens with septic shock
研究概览
简要总结
The objective of this study is to identify the types of Photoplethysmographic waves present in adults with septic shock and determine whether these waves correlate with other variables of tissue hypoperfusion such as capillary refil, serum lactate and mottling score.
详细描述
Photoplethysmography is the technology used in pulse oximeters in order to calculate arterial oxygen saturation and pulse rate, this technology generates a wave whose morphology has been related to blood flow and arterial tone. Recently Tusman and collaborators described a morphological classification of the photoplethysmografic wave that has a high correlation with arterial tone, such classification is divided in 6 types; Types I and II indicate vasoconstriction, Type III normal arterial tone and Types IV, V and VI describe mild, medium and severe vasodilation respectively, therefore it could be used to identify the arterial tone in those patients with septic shock. This study will identify the type of photoplethysmographic waves that are present in adults with septic shock based in the Tusman and collaborators classification, it will also describe the frequency of appearance and their correlation with other hemodynamic variables such as capillary refill, serum lactate, mottling score, heart rate, mean arterial pressure, pulse pressure and perfusion index.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult patients of 18 years of age and above dignossed with septic shock according to the definition stated in Sepsis 3.0
- •Patients with axillary temperature above 36°C
- •Patients and/or family that agree to participate in such study and sign the informed consentment
- •Patients that tolerate supine position
排除标准
- •Patients with Cardiogenic shock, hipovolemic, obstructive and distributive (neurogenic, anafilactic) shock the exception being septic shock
- •Patients with history of any type of cardiac arrhythmia
- •Patients with history of chronic hepatic disease
- •Patients with limited or diffuse systemic sclerosis
- •Patients that have scarring, nail polish or thickened nails that may impede the proper placement and accurate measurement of photoplethysmography with the pulse oximeter
- •Patients with history of heart insufficiency P- atients with septic shock that already have vasopressor aggents
结局指标
主要结局
Photoplethysmography wave types in adult patiens with septic shock
时间窗: After the inclusion of the patient.
The type of Photoplethysmography wave obtained and digitized through the sensor of a conventional pulse oximeter without autoscale. The wave will be classified in type I, II, III, IV, V and VI according to the criteria proposed by Tusman and collaborators
次要结局
- Capillary refill(After the inclusion of the patient)
- Mottling score(After the inclusion of the patient)
- Serum lactate levels(After the inclusion of the patient)
- Heart rate(After the inclusion of the patient)
- Sistolic and diastolic blood pressure(After the inclusion of the patient)
- Perfussion index(After the inclusion of the patien)
研究者
Juan Fernando Bautista Garcia
MD
Hospital General de México Dr. Eduardo Liceaga