NSAID Treatment of Patients With Osteoarthritis

Not Applicable

Completed

• Conditions: Osteoarthritis,Knee
• Interventions: Drug: NSAID

• Registration Number: NCT02967744
• Lead Sponsor: Aalborg University

Brief Summary

The study investigates associations between pre treatment pain intensity and central pain mechanisms on the effect of 8-week treatment of NSAIDs in patients with knee osteoarthritis.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-01
• Study First Submitted: 2016-11-14
• Study First Submitted QC: 2016-11-16
• Study First Posted: 2016-11-18
• Primary Completion: 2018-01
• Study Completion: 2018-02-01
• Status Verified: 2024-02
• Last Update Submitted: 2024-02-21
• Last Update Posted: 2024-02-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 162

Inclusion Criteria

• Diagnosed Knee Ostoarthritis

Exclusion Criteria

• Current ulcer diagnosed by endoscope
• Asthma or other allergic reaction to NSIADs
• Kidney disease
• Myocardial infarction within the last six months
• Severe hyper tension (systolic ≥180mmHg, diastolic ≥110mmHg)
• Severe thrombocytopenia (thrombocyst count <50x10^9/l)
• Insufficience lever or kidney function

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
NSAID treatment	NSAID	8 weeks of NSAID treatment

Primary Outcome Measures

Name	Time	Method
Pain intensity measured on a 10cm visual analog scale	8 weeks after treatment	Patients will be asked to rate the pain intensity 8 weeks after treatment on a 10cm visual analog scale (0 indicating no pain, 10 indicating worst imaginable pain

Trial Locations

Locations (1)

Center for Sensory Motor Interaction, Aalborg University; 🇩🇰 Aalborg East, Denmark