Randomized trial on AECOPD patients to assess efficacy of three strategies of NIV withdrawal in prevention of post extubation respiratory failure
- Conditions
- Health Condition 1: J441- Chronic obstructive pulmonary disease with (acute) exacerbation
- Registration Number
- CTRI/2022/12/048501
- Lead Sponsor
- AIIMS Rishikesh
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1.Acute exacerbation COPD patients requiring Invasive Mechanical Ventilation (IMV).
2.Planned extubation following invasive ventilation for at least 24 hours and planned to put on NIV support post extubation for any one of the above mentioned high-risk criteria
3.Acute exacerbation COPD patients on IMV fulfilling extubation criteria and passing Spontaneous breathing trial.
1.Other chest diseases (ILD, bronchiectasis, Concomitant malignancy).
2.Contraindications to NIV application (example: craniofacial trauma or surgery, ongoing upper gastrointestinal bleeding, excessive respiratory secretions or inability to handle secretion, recurrent vomiting, tracheotomised, etc.)
3.Participant denied giving a written informed consent
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method