Comparing opioid free general anesthesia to traditional balanced general anesthesia regarding achievement of enhanced recovery in laparoscopic bariatric surgeries
Phase 4
- Conditions
- Anaesthesia
- Registration Number
- PACTR202108663604989
- Lead Sponsor
- Faculty of medicine Ain shams university
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
•Undergoing a scheduled laparoscopic bariatric surgery under general anesthesia.
•Age group: 18-65 years old
•BMI 40 – 59.9 Kg/m2
Exclusion Criteria
•Pregnant or breast-feeding women
•The need to change laparoscopic surgery to an open one.
•Allergy to any of the drugs used in the study
•1st or 2nd degree Heart block
•Chronic treatment by beta-blockers
•HR < 50 bpm,
•Heart failure with LVEF < 40%,
•Epilepsy or seizures
•Alcohol or drug abuse
•Psychiatric disease
•History of chronic pain
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method oTime between the end of analgesic used and extubation<br>oTime between extubation and reaching Aldrete score of 9 (when applicable).<br>
- Secondary Outcome Measures
Name Time Method oPostoperative pain score for 48 hours using the Visual Analogue Scale (VAS),Nalbuphine consumption during the 48 hours following extubation<br><br>;oPostoperative hypoxemia.<br>•Postoperative hypoxemia is defined as peripheral oxygen saturation (SpO2) < 92% on room air with a need for oxygen supplementation; the duration of oxygen treatment will be recorded. <br>;•Number of episodes of PONV.<br>;Number of events of bradycardia, hypotension and hypertension during surgery.<br>?Bradycardia is defined as: HR=50 bpm <br>?Hypotension is defined as a decrease in systolic blood pressure >20% of basal<br>?Hypertension is defined as an increase in systolic blood pressure >20% of basal