Clinical study on the truncation and torsion effect of the Xinjia Bushen Naqi decoction combined with Liuzijue Exercise in the treatment of GOLD II - III COPD patients with decreased pulmonary ventilatio

Phase 1

• Conditions: chronic obstructive pulmonary disease

• Registration Number: ITMCTR2000003730
• Lead Sponsor: onghua Hospital Shanghai University of Traditional Chinese Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

(1) Patients who meet the diagnostic criteria of western medicine for COPD and are in the stable stage of moderate or severe COPD, and patients in group B and C who meet the criteria for comprehensive assessment of COPD;
(2) Meet the classification standard of TCM lung and kidney qi deficiency syndrome;
(3) 50 <= age <= 75, regardless of gender;
(4) Those with clear consciousness and independent judgment;
(5) Sign informed consent and agree to participate in the study.

Exclusion Criteria

(1) Patients with asthma, bronchiectasis, pulmonary cystic fibrosis, pulmonary tuberculosis, lung cancer or other known causes and restricted airflow with characteristic pathological manifestations;
(2) Exertional shortness of breath caused by coronary heart disease, heart valve disease, etc.;Combined with uremia, hyperthyroidism, heart failure;
(3) Patients with abnormal liver function (ASK, ALT more than 1.2 times of normal on-line level), or HbsAg, HbeAg and HbcAg were both positive;
(4) Uncontrolled hypertension (at rest, SBP >= 180mmHg or DBP >= 100mmHg);
(5) Patients with narrow-angle glaucoma;
(6) 18 kg/m2 <= BMI >= 25kg/m2;
(7) Complicated with severe peptic ulcer, malignant tumor, AIDS and autoimmune disease;
(8) women during pregnancy or lactation;Those with mental, intellectual and thinking abnormalities that make them unable to cooperate;
(9) persons with legal disabilities;
(10) those who have participated in or are participating in other clinical trials in the past three months;
(11) Patients who are allergic to the drugs and components used in this study and do not want to accept clinical observers.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
exercise endurance time;

Secondary Outcome Measures

Name	Time	Method
COPD assessment test;modified British medical research council;lung function;