Long-term Outcomes of Umbilical Cord Milking in Term and Late Preterm Neonates Who Are Depressed at Birth
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Hypoxic-Ischemic Encephalopathy
- Sponsor
- Nemours Children's Clinic
- Locations
- 3
- Primary Endpoint
- Neurodevelopmental Outcome at 2 Years of Age
- Status
- Withdrawn
- Last Updated
- 3 years ago
Overview
Brief Summary
An extension of the MIDAB trial, the MIDAB-Follow-up trial will evaluate the neurodevelopmental outcomes at 22-26 months age of term/late preterm infants who were depressed at birth and received umbilical cord milking (UCM) or immediate cord clamping (ICC).
Detailed Description
The MIDAB-Follow-up trial will examine the difference in survival and neurodevelopmental impairment of infants who were depressed at birth and enrolled in MIDAB trial. The difference in survival and neurodevelopmental impairment in infants who received UCM and ICC will be assessed using standardized neurological and developmental assessment tools at 22-26 months of age.
Investigators
Zubair Aghai
Professor of Pediatrics
Nemours Children's Clinic
Eligibility Criteria
Inclusion Criteria
- •Enrolled in MIDAB trial
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Neurodevelopmental Outcome at 2 Years of Age
Time Frame: 22-26 months
Overall and Domain Scores - Ages and Stages, 3rd ed. Questionnaire
Secondary Outcomes
- Fidgety Movements at 3 months of age(3-5 months)
- Neurodevelopmental Outcome at 1 Year of Age(10-14 months)
- Autism Outcome(22-26 months)