Determining the effectiveness of Remote Ischemic Postconditioning in the treatment of patients with ischemic stroke

Not Applicable

Recruiting

• Conditions: Ischemic stroke.; Other specified cerebrovascular diseases; I67.8

• Registration Number: IRCT20211226053525N1
• Lead Sponsor: Rasht University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 7 February 2022

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 160

Inclusion Criteria

No dependence on care before the stroke and MRS score <= 2
Presence of a CT SCAN or MRI indicating the occurrence of the stroke
National Institutes of Health Stroke Scale (NIHSS) score between 5 and 15 at the beginning
Less than 24 hours interval between the occurrence of the stroke and the onset of RIPC
Signed informed consent by patients or companions

Exclusion Criteria

Cerebral diseases such as intracranial aneurysm, vascular malformation and dementia
Previous brain surgery, hemorrhagic stroke or ischemic stroke in the last 3 months
Pregnancy
Severe comorbidity (incurable disease, advanced cancer with low life expectancy, renal and hepatic failure, rheumatic diseases)
Peripheral vascular disease, severe liver disease, history of chronic lung disease, liver disease, kidney disease, doctor's order

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
ational Institutes of Health Stroke Scale (NIHSS). Timepoint: On admission, at discharge and on day 90. Method of measurement: Calculation of score through questionnaire and based on patient examination.;Modified Rankin Scale (MRS). Timepoint: On admission, at discharge and on day 90. Method of measurement: Calculation of score through based on patient examination and scale.;Clinical outcome. Timepoint: at discharge. Method of measurement: Based on patients' files.;Hospital stay. Timepoint: at discharge. Method of measurement: Based on patients' files.

Secondary Outcome Measures

Name	Time	Method
Blood sugar. Timepoint: On admission, at discharge and on day 90. Method of measurement: Based on patient test results.;Blood pressure. Timepoint: On admission, at discharge and on day 90. Method of measurement: based on examination.;Blood indices: Cell blood count (CBC), Prothrombin time (PT), The international normalized ratio (INR), Partial Thromboplastin Time (PTT). Timepoint: On admission, at discharge and on day 90. Method of measurement: Based on patient test results.;Creatine kinase total. Timepoint: On admission, at discharge and on day 90. Method of measurement: Based on patient test results.;Creatinine (Cr). Timepoint: On admission, at discharge and on day 90. Method of measurement: Based on patient test results.;Liver enzymes: Aspartate aminotransferase (AST) , Alanine transaminase (ALT). Timepoint: On admission, at discharge and on day 90. Method of measurement: Based on patient test results.