Treatment of the lower limb pain, which arise during the walks, for lack of circulation. Through temporary circulation interruption of upper limbs.

Not Applicable

• Conditions: Remote Ischemic Preconditioning Intermittent ClaudicationPeripheral Arterial Disease; I73.9

• Registration Number: RBR-7tf6tm
• Lead Sponsor: Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2012-06-28
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: data analysis completed
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

this study recruited patients complaining of typical intermitent claudication (IC) in one or both lower limbs, associated with absence or reduction of arterial pulses in the symptomatic member and/or ankle-brachial index < 0.90. Physical examination of the upper limbs was normal in all study participants.

Exclusion Criteria

Arterial occlusion of both upper
Presence of critical ischemia of lower limbs, characterized by pain at rest or ischemic ulcerations existence of the same.
Inability to perform the treadmill test for reasons other than the intermittent claudication, as changes rheumatologic, orthopedic, neurological, cardiac or respiratory
Having used the following drugs in the last two hours before inclusion in the study: cilostazol, sildenafil, dipyridamole, glibenclamide, aminophylline, nicorandil, phenylephrine, angiotensin-converting enzyme inhibitors, angiotensin receptor blocker II, statins, alcohol, steroids, red wine.
Having consumed a quantity of coffee that means a caffeine intake ? 4mg/kg (approximately 400 ml of coffee brewed in coffee maker) in the last two hours prior to study entry

Study & Design

• Study Type: Intervention
• Study Design: Not specified